Iatrogenic Kaposi's sarcoma caused by corticosteroids*
نویسندگان
چکیده
To the Editor, Kaposi ́s sarcoma (KS) is a malignant neoplasm of endothelial cells with low proliferation, described by Moritz Kaposi in 1872. It is classified into four groups: endemic, reported in African regions; epidemic, which is acquired immune deficiency syndrome(AIDS)-related; classic, at first reported primarily in Ashkenazi Jews and Mediterranean peoples, indicating a genetic relationship; and iatrogenic, which affects immunosuppressed patients of autoimmune and malignant diseases, and transplanted recipients. A 36-year-old female patient was diagnosed with lepromatous leprosy in 2008. After a five-month multibacillary treatment (dapsone, rifampicin and clofazimine), erythematous and painful nodules disseminated throughout her body. Type 2 reaction was diagnosed and treated with prednisone 40 mg/day, ranging from 20-60 mg/day according to the patient’s response. Treatment lasted
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Kaposi’s sarcoma (KS) is a lymphoangioproliferative neoplasm induced by human herpes virus 8 (HHV-8). Four clinical variants have been recognized: Classical, African endemic, AIDS-related, and KS caused by iatrogenic immunosuppression. The latter is typically associated with the use of immunosuppressive therapy in organ transplant recipients; however, iatrogenic KS can also occur in patients re...
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BACKGROUND Iatrogenic Kaposi's sarcoma (KS) has been reported in patients who use immunosuppressive regimens for the treatment of autoimmune disorders, malignant neoplasms, and organ transplant rejection. However, iatrogenic KS in the setting of pemphigus vulgaris (PV) has been infrequently observed. The conventional treatment strategy for iatrogenic KS has focused on reducing immunosuppression...
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عنوان ژورنال:
دوره 91 شماره
صفحات -
تاریخ انتشار 2016